Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Researchers are studying a possible link between acetaminophen (Tylenol) use during pregnancy and higher autism or ADHD risk. It may lower glutathione, an important antioxidant for brain development. Tylenol's Impact on Glutathione and Liver Damage Tylenol lowers glutathione, which is why it can cause liver failure. Low glutathione can cause many serious health problems that can vary from person to person. Finding out if you have genes that can Acetaminophen induces liver injury and depletes glutathione in mice brain: Prevention by Moringa oleifera extract ScienceDirect Tylenol's Impact on Glutathione and Liver Damage