L carnitine: Science Backed Benefits, Risks, and More L Carnitine Benefits: A Complete Research Based Guide Early research into L carnitine was often cited as underwhelming, showing negligible changes in muscle carnitine content and fat loss outcomes. However, these findings may have been limited by a short study window Risks and benefits of carnitine supplementation in diabetes. Semantic Scholar Supplements and chronic pain: What does the research say? Some studies suggest possible benefits for: Acetyl L Carnitine (energy for cells; studied in diabetic nerve pain) Alpha Lipoic Acid (antioxidant; may ease nerve pain, Didn't another study show carnitine was good for the heart?